AlphaSim necessary when using Z-maps in SPSS?

Submitted by evast001 on Mon, 09/08/2014 - 08:30

Hi everyone

I'm using DPARSF to extract Z-maps between 8 seed regions which I then correlate in SPSS. The aim of my study is to relate resting state activity to a couple of behavioral measures. I realise that I need to conduct some form of multiple comparison correction on my correlations, but is it necessary for me to perform AlphaSim on my resting state data in DPARSF/REST before even taking it to SPSS? And if so, can someone please give me some insight on how to do this?

Thank you in advance.

/Eva

 

Forums:

YAN Chao-Gan

Mon, 09/08/2014 - 20:00

Hi Eva,

In such a case (correlations between 8 seed regions), people don't do AlphaSim or GRF correction, as those took spatial extent into account -- which you don't have.

FDR correction is more appropriate in such a case. You will need to do FDR correction among the (8*7)/2 edges.

Best,

Chao-Gan

evast001

Thu, 09/11/2014 - 07:47

Hi, Chao-Gan

Thank you for your quick reply. I must admit I'm not sure how to conduct such a correction (FDR correction among the (8*7)/2 edges). It's the edges part that I can't really wrap my head around.

/Eva

YAN Chao-Gan

Thu, 09/11/2014 - 08:30

Search fdr you can find matlab programs.

Invite 10 friends to like me @ http://facebook.com/rfmri

Show me the proof, then I will write a special program for your 28 edges.

;)

evast001

Mon, 09/15/2014 - 08:16

:-)  Sadly, I don't have any facebook friends remotely interested in MRI research... I think I will work something out.

On a completely different note, I just started looking at DPABI and it's looking really good. I'm wondering how similar it is to DPARSF? Is it possible to take files generated from DPARSF (from pre-processing for example) and put them into DPABI for various statistical analysis, or is it necessary to do everything over again using DPABI?

Thank you!

/Eva

YAN Chao-Gan

Tue, 09/16/2014 - 18:52

Hi Eva,

That doesn't matter, I am just kidding.

You can like our facebook page though: http://facebook.com/rfmri

Yes, DPABI included DPARSF as a component. Please have a look on The R-fMRI Course V2.0 at http://rfmri.org/Course

Best,

Chao-Gan